In vitro effects of artesunate on the survival of worm pairs and egg production of Schistosoma mansoni.
نویسندگان
چکیده
The effect of artesunate (ART) on the survival time of adult worm pairs of Schistosoma mansoni and on their egg output during in vitro culture was assessed. ART significantly decreased the survival time of both paired male and female worms at concentrations of 5, 10, 20 and 40 mg l- 1 during in vitro cultivation. An inhibitory effect of ART on the daily egg output of paired female worms during in vitro cultivation was also observed.
منابع مشابه
In vitro effect of current antimalarial drugs on the survival of paired Schistosoma mansoni adult worms and their egg production
Some field trials have already demonstrated the high antischistosomal potential of combination therapies using Artesunate (ART) and current antimalarial drugs (Boulanger et al., 2007; Mohamed et al., 2009; Sissoko et al., 2009). The antischistosomal effects of these drugs are noteworthy, especially when they are used for the treatment of malaria in schistosomiasis endemic areas. However, the an...
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ورودعنوان ژورنال:
- Journal of helminthology
دوره 83 1 شماره
صفحات -
تاریخ انتشار 2009